Why choose Univestin?
It’s the fast-acting, long-lasting and long-term joint solution.*
By providing rapid relief for joint discomfort and stiffness, Univestin is an innovative plant-based ingredient that meets key consumer needs.* This patent-protected ingredient:
- Is clinically shown to reduce joint stiffness within 3 days*
- Is clinically shown to reduce joint discomfort within 5 days*
- Is clinically shown to increase range of motion and physical function within 7 days*
- Supports joint health through a multi-pronged mechanism of action*
- Backed by two randomized, double-blind human clinical trials
- Is proven safe through dozens of safety studies and long-term human consumption
- Provides potent antioxidant activity*
- Promotes healthy aging and overall wellbeing*
- Undergoes stringent QA processes for guaranteed purity and potency
Additional advantages for formulators
- Combines concentrated, standardized extracts from two botanicals with long-standing use
- Is backed by solid scientific research
- Uses an all-natural aqueous extraction process
- Small dosage size (250mg/day) = small pill
- Can be used as a free-standing product or blended with other ingredients
- Has completed dozens of safety tests for a wide range of bodily systems
- Maintains rigorous quality assurance protocols and complies with all GMO regulations
- Guards against adulteration by stringent raw materials testing and identification procedures
2.Glucosamine Sulfate 750 mg
Glucosamine sulfate, glucosamine hydrochloride, N-acetyl glucosamine
Origin: Major component of joint cartilage. Supplements are derived from the shells of shellfish (such as shrimp, lobster and crab) or from vegetable sources.
Dosage: Capsules, tablets, liquid or powder (to be mixed into a drink); 1,500 mg per day for all forms. Often combined with chondroitin. May take one month to notice effect.
Claims: Slows deterioration of cartilage, relieves osteoarthritis(OA) pain and improves joint mobility.
What we know: Glucosamine produced in the body provides natural building blocks for growth, repair and maintenance of cartilage. Like chondroitin, glucosamine may lubricate joints, help cartilage retain water and prevent its breakdown. Similar to NSAIDs for effectiveness of easing osteoarthritis symptoms but may take twice as long as conventional drugs to work.
Studies: Trial results are mixed, but overall, glucosamine appears to reduce pain and improve function in OA. A 2005 review of 20 glucosamine studies found an improvement in joint pain, stiffness and function with one brand of glucosamine (Rottapharm, marketed as Dona, Viartril and Xicil) but not others.
The largest study to date, the 2006 Glucosamine/chondroitin Arthritis Intervention Trial (GAIT) looked at 1,600 people with knee OA. The first phase found that a small subset of patients with moderate-to-severe arthritis experienced significant pain relief from combined glucosamine and chondroitin. The 2008 phase found that glucosamine and chondroitin, together or alone, did not slow joint damage. And in the two-year-long 2010 phase, glucosamine and chondroitin were found as effective for knee OA as celecoxib (Celebrex).
In a small 2012 study, an improvement in symptoms was seen with combined glucosamine and NSAIDs, and a smaller but still significant improvement with glucosamine alone.
Research also suggests glucosamine may slow joint damage. A 2008 retrospective study of nearly 300 patients found those using glucosamine underwent half as many joint replacement surgeries as those on placebo.
Dosage: Capsules, tablets, liquid or powder (to be mixed into a drink); 1,500 mg once daily or in three divided doses to prevent stomach upset. Often combined with chondroitin. May take up to one month to notice effect.
Glucosamine may cause mild stomach upset, nausea, heartburn, diarrhea and constipation, as well as increased blood glucose, cholesterol, triglyceride and blood pressure. Don’t use glucosamine if you are allergic to shellfish.
New research suggests that people with glaucoma or intraocular hypertension could have worsening eye pressure if they take a glucosamine supplement.
3.Chondrotin Sulfate 200mg
Origin: Chondroitin is a component of human connective tissues found in cartilage and bone. In supplements, chondroitin sulfate usually comes from animal cartilage.
Claims: Reduces pain and inflammation, improves joint function and slows progression of osteoarthritis (OA).
What we know: Believed to enhance the shock-absorbing properties of collagen and block enzymes that break down cartilage. Helps cartilage retain water and may reverse cartilage loss when used with glucosamine.
Studies: The largest study to date, the 2006 Glucosamine/chondroitin Arthritis Intervention Trial (GAIT) looked at 1,600 people with knee OA. The first phase found that a small subset of patients with moderate-to-severe arthritis experienced significant pain relief from combined glucosamine and chondroitin. The 2008 phase found that glucosamine and chondroitin, together or alone, did not slow joint damage. And in the two-year-long 2010 phase, glucosamine and chondroitin were found as effective for knee OA as celecoxib (Celebrex).
But a 2010 meta-analysis of 10 trials involving more than 3,000 patients published in BMJ found no benefit from chondroitin, glucosamine or both.
A separate 2011 study showed a significant improvement in pain and function in patients with hand OA using chondroitin alone. Benefits of chondroitin and glucosamine remain controversial, but the supplements appear extremely safe.
Dosage: Capsules, tablets and powder; 800 mg to 1,200 mg daily in two to four divided doses. Often combined with glucosamine. Allow up to one month to notice effect.
4.Methyl Sulphonyl Methane 250mg
Methylsulfonylmethane (MSM) is a chemical found in green plants, animals, and humans. It can also be made in a laboratory. MSM has become popular because of the book The Miracle of MSM: The Natural Solution for Pain. But there is little published scientific research to support its use. Contrary to some literature that promotes MSM, there is no Recommended Dietary Allowance (RDA) for MSM or sulfur, which is in MSM. Sulfur deficiency has not been described in the medical literature.
People take MSM by mouth and apply it to the skin for chronic pain, osteoarthritis, joint inflammation, rheumatoid arthritis, osteoporosis, inflammation around the joints (bursitis), tendinitis, swelling around the tendons (tenosynovitis), musculoskeletal pain, muscle cramps, hardened skin condition called scleroderma, scar tissue, stretch marks, hair loss, wrinkles, protection against sun/wind burn, eye inflammation, oral hygiene, gum disease, wounds, cuts, and abrasions/accelerated wound healing.
People also take MSM by mouth for relief of allergies, chronic constipation, “sour stomach”, ulcers, a bowel disease called diverticulosis, premenstrual syndrome (PMS), mood elevation, obesity, poor circulation, high blood pressure, and high cholesterol. It is also taken by mouth for type 2 diabetes, liver problems, Alzheimer’s disease, to control snoring, lung disorders including emphysema and pneumonia, chronic fatigue syndrome, autoimmune disorders (systemic lupus erythematous), HIV infection and AIDS, and cancer (breast cancer and colon cancer).
MSM is also taken by mouth for eye inflammation, mucous membrane inflammation, temporomandibular joint (TMJ) problems, leg cramps, migraine, headaches, hangover, parasitic infections of the intestinal and urogenital tracts including Trichomonas vaginalis and Giardia, yeast infection, insect bites, radiation poisoning, and to boost the immune system.
5.Vitamin D3 1000 I.U
What Is Vitamin D3 (Cholecalciferol)?
Vitamin D3 is the common name for cholecalciferol.
Vitamin D3 can be taken as a supplement to improve overall health or used to treat osteoporosis.
It can also be used to treat conditions in which vitamin D3 levels may be low, such as in people who have underactive parathyroid glands, low levels of phosphate in the blood, or hereditary conditions in which the body doesn’t respond to the parathyroid hormone.
Vitamin D3 also encourages the kidneys to recycle phosphate back into the blood, which helps the blood stay at the right pH.
Vitamin D3 is available for purchase over-the-counter (OTC).
Vitamin D3 Deficiency
Historically, vitamin D3 loss has been associated with rickets, a disease caused by low levels of vitamin D3 that commonly affects children.
Children with rickets and adults who had rickets as children often have legs that are bow-shaped.
However, while adults who are deficient in vitamin D3 do not typically develop rickets disease, their bones may start to become softer — a condition known as osteomalacia.
Sunlight is a natural source of vitamin D3, and people who rarely or never go outside (for example, those in nursing homes or bedridden hospital patients) are most likely to be deficient in it.
Also, the darker your skin, the more sunlight you need to keep vitamin D3 at healthy levels.
This is because the extra melanin found in darker skin slows the absorption of vitamin D3.
Some studies suggest that the time of day when you receive sunlight affects how well your body absorbs vitamin D3.
While many experts advise people to avoid sunlight between the hours of 10 AM and 2 PM or 3 PM to help protect their skin from cancer, data shows the body actually absorbs vitamin D3 better during this time.
The Difference Between Vitamin D2 and Vitamin D3
There are two forms of vitamin D: Vitamin D2, or ergocalciferol, is commonly found in foods.
Vitamin D3 is made by the body naturally when skin is exposed to the sun.
Although there is some debate, most experts currently believe that the best form of vitamin D supplement to take is vitamin D3.
It’s thought that D3 is more natural and easier for the body to absorb.
Also, the body does not allow as large a concentration of D3 to circulate in the bloodstream as it does D2, so it’s considered safer.
Vitamin D Foods
Oily fish like salmon, codfish, mackerel, and blue fish are great natural sources of vitamin D.
Fortified foods — such as milk and cereal — along with egg yolks and raw shiitake mushrooms also contain vitamin D.
Vitamin D3 and Acne
There is some debate about whether vitamin D3 works to treat acne.
The Vitamin D Council website states that lack of sunlight may increase acne, and some people notice their acne worsening during the winter and improving during the summer.
Still, there aren’t any clinical studies supporting the use of vitamin D3 for acne.
There’s also very little evidence supporting the use of vitamin D in preventing acne.
However, some anecdotal reports claim that acne improved after taking vitamin D supplements or applying it (in oil form) to their skin.
Vitamin D3 Levels and Weight
Recent studies show that people who are overweight may have higher levels of vitamin D.
The reason is thought to be because vitamin D is an oily substance that tends to get stored in the body’s fat tissue.
So, the more body fat you have, the more easily the body can store vitamin D.
If you are underweight, your levels may be lower than you’d expect because you have less body fat in which to store extra vitamin D.